Herbert Virgin: search on Z-Library

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1

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

Doench, John G, Fusi, Nicolo, Sullender, Meagan, Hegde, Mudra, Vaimberg, Emma W, Donovan, Katherine F, Smith, Ian, Tothova, Zuzana, Wilen, Craig, Orchard, Robert, Virgin, Herbert W, Listgarten, Jennif

Journal:

Nature Biotechnology

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

2

The Virome in Mammalian Physiology and Disease

Virgin, Herbert W.

Journal:

Year:

2014

Language:

english

File:

PDF, 806 KB

english, 2014

3

Reservoir Host Immune Responses to Emerging Zoonotic Viruses

Mandl, Judith N., Ahmed, Rafi, Barreiro, Luis B., Daszak, Peter, Epstein, Jonathan H., Virgin, Herbert W., Feinberg, Mark B.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.96 MB

english, 2015

4

High throughput screen identifies IFN-γ-dependent inhibitors of Toxoplasma gondii growth

Radke, Joshua B, Carey, Kimberly L, Shaw, Subrata, Metkar, Shailesh, Mulrooney, Carol, Gale, Jennifer P, Bittker, Joshua A., Hilgraf, Robert, Comer, Eamon, Schreiber, Stuart L, Virgin, Herbert W., Per

Journal:

ACS Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 1.39 MB

english, 2018

5

Drowning in Viruses

Handley, Scott A., Virgin, Herbert W.

Journal:

Year:

2019

Language:

english

File:

PDF, 527 KB

english, 2019

6

Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier

Loh, Joy, Barton, Erik, Virgin, Herbert W, McFadden, Grant, Wang, Fuan, Ma, Yiyue, Barrett, John W, Gao, Xiujuan

Journal:

Nature Immunology

Year:

2004

Language:

english

File:

PDF, 636 KB

english, 2004

7

In vivo veritas: pathogenesis of infection as it actually happens

'Skip' Virgin, Herbert W

Journal:

Nature Immunology

Year:

2007

Language:

english

File:

PDF, 1019 KB

english, 2007

8

Unraveling immunity to γ-herpesviruses: a new model for understanding the role of immunity in chronic virus infection

Herbert W. Virgin IV, Samuel H. Speckt

Journal:

Current Opinion in Immunology

Year:

1999

Language:

english

File:

PDF, 1.16 MB

english, 1999

9

Delivery of Cytosolic Components by Autophagic Adaptor Protein p62 Endows Autophagosomes with Unique Antimicrobial Properties

Marisa Ponpuak, Alexander S. Davis, Esteban A. Roberts, Monica A. Delgado, Christina Dinkins, Zijiang Zhao, Herbert W. Virgin IV, George B. Kyei, Terje Johansen, Isabelle Vergne, Vojo Deretic

Journal:

Year:

2010

Language:

english

File:

PDF, 1.50 MB

english, 2010

10

Herpesvirus latency confers symbiotic protection from bacterial infection

Barton, Erik S., White, Douglas W., Cathelyn, Jason S., Brett-McClellan, Kelly A., Engle, Michael, Diamond, Michael S., Miller, Virginia L., Virgin, Herbert W.

Journal:

Year:

2007

Language:

english

File:

PDF, 433 KB

english, 2007

11

Immunology and the elusive AIDS vaccine

Virgin, Herbert W., Walker, Bruce D.

Journal:

Year:

2010

Language:

english

File:

PDF, 7.62 MB

english, 2010

12

Autophagy in immunity and inflammation

Levine, Beth, Mizushima, Noboru, Virgin, Herbert W.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.30 MB

english, 2011

13

Autophagy genes in immunity

Levine, Beth, Virgin, Herbert W

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 1.44 MB

english, 2009

14

A 'fly-by' killing with a primordial cellular weapon

Virgin, Herbert

Journal:

Nature Immunology

Year:

2008

Language:

english

File:

PDF, 567 KB

english, 2008

15

Reply to “Viruses and vascular disease“

Speck, Samuel H., Virgin, Herbert W.

Journal:

Nature Medicine

Year:

1998

File:

PDF, 379 KB

1998

16

Murine γ-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-γ responsiveness: A new model for virus-induced vascular disease

Weck, Karen E., Dal Canto, Albert J., Gould, James D., O'Guin, Andrew K., Roth, Kevin A., Saffitz, Jeffrey E., Speck, Samuel H., Virgin, Herbert W.

Journal:

Nature Medicine

Year:

1997

File:

PDF, 1022 KB

1997

17

Immune regulation of viral infection and vice versa

Herbert W. Virgin

Journal:

Immunologic Research

Year:

2005

Language:

english

File:

PDF, 578 KB

english, 2005

18

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells

Nadia V. Giannakopoulos, Jiann-Kae Luo, Vladimir Papov, Weiguo Zou, Deborah J. Lenschow, Barbara S. Jacobs, Ernest C. Borden, Jun Li, Herbert W. Virgin, Dong-Er Zhang

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 8 KB

english, 2005

19

Latent Murine Cytomegalovirus Infection in Macrophages

JESSICA L. POLLOCK, RACHEL M. PRESTI, SUSANNE PAETZOLD, HERBERT W. VIRGIN IVth

Journal:

Year:

1997

Language:

english

File:

PDF, 172 KB

english, 1997

20

Murine Cytomegalovirus Infection Inhibits IFNγ-Induced MHC Class II Expression on Macrophages: The Role of Type I Interferon

Mark T. Heise, Jessica L. Pollock, Andrew O'Guin, Melissa L. Barkon, Shannon Bromley, Herbert W. Virgin IV

Journal:

Year:

1998

Language:

english

File:

PDF, 326 KB

english, 1998

21

CD4 T cell control of acute and latent murine gammaherpesvirus infection requires IFNγ

Rebecca L. Sparks-Thissen, Douglas C. Braaten, Kai Hildner, Theresa L. Murphy, Kenneth M. Murphy, Herbert W. Virgin IV

Journal:

Year:

2005

Language:

english

File:

PDF, 358 KB

english, 2005

22

A γ-herpesvirus deficient in replication establishes chronic infection in vivo and is impervious to restriction by adaptive immune cells

Scott A. Tibbetts, Felipe Suarez, Ashley L. Steed, Jacob A. Simmons, Herbert W. Virgin IV

Journal:

Year:

2006

Language:

english

File:

PDF, 435 KB

english, 2006

23

MHV68 complement regulatory protein facilitates MHV68 replication in primary macrophages in a complement independent manner

Vera L. Tarakanova, Jerome M. Molleston, Megan Goodwin, Herbert W. Virgin IV

Journal:

Year:

2010

Language:

english

File:

PDF, 677 KB

english, 2010

24

Disruption of the gene encoding the γHV68 v-GPCR leads to decreased efficiency of reactivation from latency

Nathaniel J Moorman, Herbert W Virgin IV, Samuel H Speck

Journal:

Year:

2003

Language:

english

File:

PDF, 410 KB

english, 2003

25

Mechanism of interferon-gamma (IFNγ) action during acute and latent murine cytomegalovirus (MCMV) infection

Journal:

Journal of Clinical Virology

Year:

1999

Language:

english

File:

PDF, 91 KB

english, 1999

26

Redefining Chronic Viral Infection

Herbert W. Virgin, E. John Wherry, Rafi Ahmed

Journal:

Year:

2009

Language:

english

File:

PDF, 2.70 MB

english, 2009

27

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

Ken Cadwell, Khushbu K. Patel, Nicole S. Maloney, Ta-Chiang Liu, Aylwin C.Y. Ng, Chad E. Storer, Richard D. Head, Ramnik Xavier, Thaddeus S. Stappenbeck, Herbert W. Virgin

Journal:

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

28

Metagenomics and Personalized Medicine

Herbert W. Virgin, John A. Todd

Journal:

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

29

γ-Herpesvirus Kinase Actively Initiates a DNA Damage Response by Inducing Phosphorylation of H2AX to Foster Viral Replication

Vera L. Tarakanova, Van Leung-Pineda, Seungmin Hwang, Chiao-Wen Yang, Katie Matatall, Mickael Basson, Ren Sun, Helen Piwnica-Worms, Barry P. Sleckman, Herbert W. Virgin IV

Journal:

Cell Host & Microbe

Year:

2007

Language:

english

File:

PDF, 897 KB

english, 2007

30

Redefining the Genetics of Murine Gammaherpesvirus 68 via Transcriptome-Based Annotation

L. Steven Johnson, Erin K. Willert, Herbert W. Virgin

Journal:

Cell Host & Microbe

Year:

2010

Language:

english

File:

PDF, 822 KB

english, 2010

31

Selective Subversion of Autophagy Complexes Facilitates Completion of the Brucella Intracellular Cycle

Tregei Starr, Robert Child, Tara D. Wehrly, Bryan Hansen, Seungmin Hwang, Carlos López-Otin, Herbert W. Virgin, Jean Celli

Journal:

Cell Host & Microbe

Year:

2012

Language:

english

File:

PDF, 3.12 MB

english, 2012

32

Autophagy Links Inflammasomes to Atherosclerotic Progression

Babak Razani, Chu Feng, Trey Coleman, Roy Emanuel, Haitao Wen, Seungmin Hwang, Jenny P. Ting, Herbert W. Virgin, Michael B. Kastan, Clay F. Semenkovich

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

33

CS08-3. ISG54 protects mice against VSV pathogenesis

Volker Fensterl, Jaime L. Rupert, Srividya Ramachandran, Stephen A. Stohlman, Herbert W. Virgin, Ganes C. Sen

Journal:

Year:

2011

Language:

english

File:

PDF, 132 KB

english, 2011

34

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

Carl J. DeSelm, Brian C. Miller, Wei Zou, Wandy L. Beatty, Eline van Meel, Yoshifumi Takahata, Judith Klumperman, Sharon A. Tooze, Steven L. Teitelbaum, Herbert W. Virgin

Journal:

Developmental Cell

Year:

2011

Language:

english

File:

PDF, 921 KB

english, 2011

35

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

Carl J. DeSelm, Brian C. Miller, Wei Zou, Wandy L. Beatty, Eline van Meel, Yoshifumi Takahata, Judith Klumperman, Sharon A. Tooze, Steven L. Teitelbaum, Herbert W. Virgin

Journal:

Developmental Cell

Year:

2011

Language:

english

File:

PDF, 36 KB

english, 2011

36

Solution Structure of the BHRF1 Protein From Epstein-Barr Virus, a Homolog of Human Bcl-2

Qiulong Huang, Andrew M. Petros, Herbert W. Virgin, Stephen W. Fesik, Edward T. Olejniczak

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.02 MB

english, 2003

37

Structural Basis of Chemokine Sequestration by a Herpesvirus Decoy Receptor

Jennifer M. Alexander, Christopher A. Nelson, Victor van Berkel, Elaine K. Lau, Joey M. Studts, Tom J. Brett, Samuel H. Speck, Tracy M. Handel, Herbert W. Virgin, Daved H. Fremont

Journal:

Year:

2002

Language:

english

File:

PDF, 1.13 MB

english, 2002

38

Animal models of infection-mediated vasculitis: implications for human disease

Albert J Dal Canto, Herbert W Virgin IV

Journal:

International Journal of Cardiology

Year:

2000

Language:

english

File:

PDF, 575 KB

english, 2000

39

Virus Subversion of the MHC Class I Peptide-Loading Complex

Lonnie Lybarger, Xiaoli Wang, Michael R Harris, Herbert W Virgin IV, Ted H Hansen

Journal:

Year:

2003

Language:

english

File:

PDF, 420 KB

english, 2003

40

Critical Role of Complement and Viral Evasion of Complement in Acute, Persistent, and Latent γ-Herpesvirus Infection

Sharookh B. Kapadia, Beth Levine, Samuel H. Speck, Herbert W. Virgin IV

Journal:

Year:

2002

Language:

english

File:

PDF, 2.99 MB

english, 2002

41

Host and viral genetics of chronic infection: a mouse model of gamma-herpesvirus pathogenesis

Samuel H Speck, Herbert W Virgin IV

Journal:

Current Opinion in Microbiology

Year:

1999

Language:

english

File:

PDF, 863 KB

english, 1999

42

IMMUNE COMPLEXES SUPPRESS CELLULAR IMMUNITY

Herbert W. Virgin IV, Emil R. Unanue

Journal:

Annals of the New York Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 780 KB

english, 1984

43

Identification of a candidate therapeutic autophagy-inducing peptide

Shoji-Kawata, Sanae, Sumpter, Rhea, Leveno, Matthew, Campbell, Grant R., Zou, Zhongju, Kinch, Lisa, Wilkins, Angela D., Sun, Qihua, Pallauf, Kathrin, MacDuff, Donna, Huerta, Carlos, Virgin, Herbert W.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.23 MB

english, 2013

44

Kingdom-Agnostic Metagenomics and the Importance of Complete Characterization of Enteric Microbial Communities

Norman, Jason M., Handley, Scott A., Virgin, Herbert W.

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 954 KB

english, 2014

45

The F rancisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance

Case, Elizabeth Di Russo, Chong, Audrey, Wehrly, Tara D., Hansen, Bryan, Child, Robert, Hwang, Seungmin, Virgin, Herbert W., Celli, Jean

Journal:

Cellular Microbiology

Year:

2014

Language:

english

File:

PDF, 1.08 MB

english, 2014

46

40

Chen, Hao, Zheng, Donghang, Liu, Liying, Bartee, Mee Y., Davids, Jennifer, Macaulay, Colin, Strong, Jim, Feldmann, Heinz, McFadden, Grant, Lomas, David A., Virgin, Herbert W., Lucas, Alexandra

Journal:

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

47

Advances in Norovirus Biology

Karst, Stephanie M., Wobus, Christiane E., Goodfellow, Ian G., Green, Kim Y., Virgin, Herbert W.

Journal:

Cell Host & Microbe

Year:

2014

Language:

english

File:

PDF, 1.02 MB

english, 2014

48

Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway

Chong, Audrey, Wehrly, Tara D., Child, Robert, Hansen, Bryan, Hwang, Seungmin, Virgin, Herbert W., Celli, Jean

Journal:

Year:

2012

Language:

english

File:

PDF, 4.22 MB

english, 2012

49

Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain

Borin, Brendan N., Tang, Wei, Nice, Timothy J., McCune, Broc T., Virgin, Herbert W., Krezel, Andrzej M.

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2014

Language:

english

File:

PDF, 900 KB

english, 2014

50

Herpesvirus Latency and Symbiotic Protection from Bacterial Infection

Barton, Erik S., White, Douglas W., Virgin, Herbert W.

Journal:

Viral Immunology

Year:

2009

Language:

english

File:

PDF, 48 KB

english, 2009

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